If you ever get the lucky chance to join the 250-mile-high club, you will obviously have to make a lot of practical considerations before getting down to business. Your freeze dried, nutrient-packed mush might not be the perfect romantic meal, and mission control watching you might be a bit of a mood kill, but your main concern is the weightlessness you will experience in space.
In this video from National Geographic, Neil deGrasse Tyson has all the answers you could want, without too much explicit detail. The solution, according to deGrasse Tyson, is lots of straps. Although fluffy handcuffs could work, too.