Particles From Polluted Air Have Been Detected In The Placenta For The First Time

London exceeded its annual air pollution limit in just a month. Adam Cowell/Shutterstock

Rosie McCall 17 Sep 2018, 16:43

It's no secret that a mother's exposure to pollution can harm her unborn child. Studies have linked polluted air to many a health problem, including premature birthlow birth weight, and infant mortality as well as childhood obesity, high blood pressurerespiratory problems, and brain abnormalities.

Now, we might be closer to understanding why. For the very first time, researchers have found evidence that microscopic carbon particles find their way to the placenta. 

The research was presented last week at the European Respiratory Society International Congress in Paris, France, by Norrice Liu, a pediatrician and clinical research fellow, and Lisa Miyashita, a post-doctoral researcher. Both are members of Professor Jonathan Grigg's research group at Queen Mary University of London.

The researchers came to this discovery after examining the placentas of five women post-birth. The women were non-smokers who had undergone a C-section and they each lived in London, a city so polluted that it breached its annual air pollution limit within the first month of 2018. (Believe it or not, this is an improvement on the previous year, which saw pollution exceed the annual limit after just five days.)

From these five placentas, the researchers identified 3,500 placental macrophage cells. These cells are responsible for swallowing toxic particles, whether it's bacteria or pollution, and can be found across the body – not just in the placenta.

It turned out, each placenta contained an average of roughly 5 square micrometers of a black substance the researchers believe to be carbon particles. In total, they singled out 60 cells with 72 small black areas across the five placentas. 

"We've known for a while that air pollution affects fetal development and can continue to affect babies after birth and throughout their lives," Miyashita said in a statement.

"We were interested to see if these effects could be due to pollution particles moving from the mother's lungs to the placenta. Until now, there has been very little evidence that inhaled particles get into the blood from the lung."

Next, they studied two placentas in even greater detail with an electron microscope. They found more of the same black substance.

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